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廖晓阳, 张薇, 王伟文等. 成都农村务农人群糖尿病和糖尿病前期血脂水平的研究[J]. koko体育app 学报（医学版）, 2014, 45(3): 447-450.
引用本文: 廖晓阳, 张薇, 王伟文等. 南京中国农村农务客群尿毒症和尿毒症的早期高血脂水平方向的学习[J]. 山东二本大学学报（医美版）, 2014, 45(3): 447-450.
LIAO Xiao-yang, ZHANG Wei, WANG Wei-wen.et al. Levels of Serum Lipids in Rural Populations with Diabetes and Pre-diabetes in Chengdu[J]. Journal of Sichuan University (Medical Sciences), 2014, 45(3): 447-450.
Citation: LIAO Xiao-yang, ZHANG Wei, WANG Wei-wen.et al. Levels of Serum Lipids in Rural Populations with Diabetes and Pre-diabetes in Chengdu[J]. Journal of Sichuan University (Medical Sciences), 2014, 45(3): 447-450.

成都农村务农人群糖尿病和糖尿病前期血脂水平的研究

Levels of Serum Lipids in Rural Populations with Diabetes and Pre-diabetes in Chengdu

  • 摘要: 目的 调查分析成都市农村务农人群糖尿病和糖尿病前期患者及其血脂水平特点。 方法 选择距离城市中心100公里外某农村，采取随机整群抽样方法，对当地35~70岁务农人员进行问卷调查、体格检查和实验室检查。予以口服75 g葡萄糖耐量试验（OGTT），根据OGTT结果分为5个不同糖代谢组别〔单纯空腹血糖受损（IFG）组、单纯糖耐量异常（IGT）组、IFG+IGT组、糖尿病（DM）组和糖耐量正常（NGT）组〕，同时检测血脂即总胆固醇(TC) 、血清甘油三脂(TG) 、高密度脂蛋白胆固醇(HDL-c) 、低密度脂蛋白胆固醇(LDL-c)。 结果 共调查成都农村35~70岁务农村民971例，糖尿病和糖尿病前期总患病率分别为12.8%和34.5%。男性和女性患病率差异均无统计学意义。糖耐量异常是糖尿病前期中最常见的类型。糖尿病患者合并高TG者占45.9%,合并高LDL-c者占30.6%，合并低HDL-c者占9.9%。女性合并高TG者及合并高LDL-c者的比例高于男性，差异有统计学意义。糖尿病前期人群合并高LDL-c者占38.1%，合并高TG者占30.6%，合并高血压者占23.9%，合并低HDL-c者占7.6%。血LDL-c、TG水平在正常血糖、糖尿病前期和糖尿病人群逐渐增高。糖尿病患者高LDL-c、TG和低HDL-c水平与NGT组相比差异有统计学意义。糖尿病前期IFG+IGT人群LDL-c、TG水平也高于NGT组。 结论 成都市农村务农人员糖尿病和糖尿病前期患病率较高，且合并不同程度的血脂代谢异常。  
    Abstract: Objective To investigate the serum lipid levels in rural residents with diabetes and pre-diabetes conditions in Chengdu. Methods Random cluster sampling method was employed to select participants of 35-70 year-old rural residents in Chengdu. The participants (n=971) were given standard 75 g oral glucose tolerance tests (OGTT) and divided into five groups: impaired fasting glucose (IFG) group, impaired glucose tolerance (IGT) group, IFG and IGT(IFG+IGT) group, diabetes mellitus (DM) group and normal glucose tolerance (NGT) group. Their serum total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c) and low density lipoprotein cholesterol (LDL-c) were measured. Results The age-adjusted standardized prevalence of DM and pre-diabetes in rural residents in Chengdu were 12.8% and 34.5%, respectively, without significant gender differences. IGT was the most common type of abnormal glucose metabolism in pre-diabetes. High serum TG and LDL-c and low serum HDL-c were found in 45.9%, 30.6% and 9.9% participants with DM, respectively. High serum LDL-c and TG and low serum HDL-c were found in 38.1%, 30.6% and 7.6% of participants with IGR. Participants with DM or/and IGR had higher levels of LDL-c and TG and lower levels of HDL-c than those in the NGT group. Conclusion Pre-diabetes and diabetes are prevalent in rural residents in Chengdu, which are usually accompanied with various degrees of dyslipidemia.  
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