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谢和平, 刘吉峰, 高明忠等. 深地医学研究进展及构想[J]. koko体育app 学报(医学版), 2018, 49(2): 163-168.
引用本文: 谢友好, 刘吉峰, 很高忠等. 深地医药学论述近况及指导思想[J]. 广东大专学报(医药学版), 2018, 49(2): 163-168.
XIE He-ping, LIU Ji-feng, GAO Ming-zhong. et al. The Research Advancement and Conception of the Deep-underground Medicine[J]. Journal of Sichuan University (Medical Sciences), 2018, 49(2): 163-168.
Citation: XIE He-ping, LIU Ji-feng, GAO Ming-zhong. et al. The Research Advancement and Conception of the Deep-underground Medicine[J]. Journal of Sichuan University (Medical Sciences), 2018, 49(2): 163-168.

深地医学研究进展及构想

The Research Advancement and Conception of the Deep-underground Medicine

  • 摘要: 21世纪是开发利用地下空间的世纪,可预见未来人类在地下空间生活与工作占比时间会越来越多,然而地下空间环境对人类健康的影响程度及其机制研究依然空白。本文系统提出深地医学研究的战略构想,以期揭示地下空间环境对生命体生理和病理,以及对人心理的影响及机制,并研究应对策略。本文系统概括了深地医学研究进展及构想,构建的研究方向主要包括:①不同深度地下空间人居环境参数(温度、辐射、气压、围岩性质、微生物等)的模型构建、定量表征及其对人类健康的影响及其机制;②深地环境下生物机体的生理功能改变、稳态维持和生物节律模式;③不同岩层、岩性的物性特征对人类健康的影响及其机制,分析地下区域岩性环境变迁对生物体的生长贡献模式;④地下空间的建造深度、结构类型、物理环境及作业时间与人类心理健康之间的关联关系;⑤深地环境下细胞生长、代谢及能量交换规律、应答反应、生长响应、衰老和适应机制;⑥深地环境下微生物的生理特征、发育变化以及与宿主的相互作用机制;⑦深地模拟舱及深地环境下生物医学技术、设备研发。课题组在岩层覆盖厚度达1 470 m地下建成世界上第一个深地医学实验室,并已开展多个不同深度水平深地医学的相关测试与分析。  
    Abstract: The 21th century is the century of exploring and utilizing the underground space. In the future,more and more people will spend more and more time living or/and working in the underground space. However, we know little about the effect on the health of human caused by the underground environment. Herein, we systematically put forward the strategic conception of the deep-underground medicine, in order to reveal relative effects and mechanism of the potential factors in the deep underground space on human’s physiological and psychological healthy, and to work out the corresponding countermeasures. The original deep-underground medicine includes the following items. ①To model different depth of underground environment according to various parameters (such as temperature, radiation, air pressure,rock, microorganism),and to explore their quantitative character and effects on human health and mechanism. ② To study the psychological change,maintenance of homeostasis and biothythm of organism in the deep underground space. ③ To learn the association between psychological healthy of human and the depth,structure,physical environment and working time of underground space. ④ To investigate the effect of different terrane and lithology on healthy of human and to deliberate their contribution on organism growth. ⑤ To research the character and their mechanism of growth, metabolism, exchange of energy, response of growth,aging and adaptation of cells living in deep underground space. ⑥ To explore the physiological feature, growth of microbiome and it’s interaction with host in the deep underground space. ⑦ To develop deep-underground simulation space,the biologically medical technology and equipments. As a research basis, a deep-underground medical lab under a rock thickness of about 1 470 m has been built, which aims to operate the research of the effect on living organism caused by different depth of underground environment.  
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