koko体育app

欢迎来到《koko体育app 学报（医学版）》
刘小锦, 李文龙, 彭友悦等. 四川省绵阳市1～12岁koko体育app 乙肝表面抗原和乙肝表面抗体的分布现况[J]. koko体育app 学报（医学版）, 2018, 49(2): 304-308.
引用本文: 刘小锦, 李文龙, 彭友悦等. 河南省成都市市1～13岁koko体育app 乙型肝炎病表层抗原和乙型肝炎病表层抗原的规划现况[J]. 河南师范大学学报（分子生物学版）, 2018, 49(2): 304-308.
LIU Xiao-jin, LI Wen-long, PENG You-yue. et al. Prevalence of Hepatitis B Surface Antigens and Hepatitis B Surface Antibodies in 1-12 Years-old Children in Mianyang, Sichuan[J]. Journal of Sichuan University (Medical Sciences), 2018, 49(2): 304-308.
Citation: LIU Xiao-jin, LI Wen-long, PENG You-yue. et al. Prevalence of Hepatitis B Surface Antigens and Hepatitis B Surface Antibodies in 1-12 Years-old Children in Mianyang, Sichuan[J]. Journal of Sichuan University (Medical Sciences), 2018, 49(2): 304-308.

四川省绵阳市1～12岁koko体育app 乙肝表面抗原和乙肝表面抗体的分布现况

Prevalence of Hepatitis B Surface Antigens and Hepatitis B Surface Antibodies in 1-12 Years-old Children in Mianyang, Sichuan

  • 摘要: 目的了解四川省绵阳市1～12岁koko体育app 乙肝表面抗原（HBsAg）和乙肝表面抗体（抗-HBs）的分布现况，为制定和完善koko体育app 乙肝疫苗免疫规划策略提供依据。方法2015年1～12月，采用多阶段分层随机整群抽样方法，抽取绵阳市乙肝计划免疫实施后出生的1～12岁koko体育app 72 623名，对其进行个人信息采集和血标本采集，用ELISA法检测血清HBsAg和抗-HBs，对HBsAg阳性者进行复检。结果绵阳市1～12岁koko体育app 的HBsAg阳性率为0.24%，抗-HBs阳性率为64.50%，HBsAg与抗-HBs双阴性率为35.26%，根据2010年全国第六次人口普查标准化率分别为0.24%、64.05%和35.71%。1～12岁各年龄组koko体育app 的HBsAg阳性率为0%~0.65%，随着年龄增大呈升高趋势（P<0.001），农村koko体育app HBsAg阳性率（0.32%）高于城市koko体育app （0.16%，P<0.001），有乙肝家族史koko体育app HBsAg阳性率（1.53%）高于无家族史koko体育app （0.22%，P<0.001）；1～12岁各年龄组koko体育app 的抗-HBs阳性率为47.85%~71.43%，随着年龄增大呈降低趋势（P<0.001），农村koko体育app 抗-HBs阳性率（62.06%）低于城市koko体育app （66.81%，P<0.001）；1～12岁各年龄组koko体育app HBsAg与抗-HBs双阴性率为28.57%~51.98%，随着年龄增大呈升高趋势（P<0.001）,农村koko体育app HBsAg与抗-HBs双阴性率（37.62%）高于城市koko体育app （33.03%，P<0.001），无乙肝免疫史koko体育app HBsAg与抗-HBs双阴性率为35.37%。结论绵阳市乙肝计划免疫工作取得显著成效，但不同特征koko体育app 抗-HBs阳性率存在差异，乙型肝炎病毒易感koko体育app 仍占一定比例，应重视新生儿乙肝疫苗的接种，积极开展koko体育app 抗-HBs水平监测，对缺乏抗体保护的koko体育app 实施加强免疫。  
    Abstract: Objective To determine the prevalence of hepatitis B surface antigens (HBsAg) and hepatitis B surface antibodies (anti-HBs) in 1-12 years-old children in Mianyang city, Sichuan Province. Methods Children born after the implementation of Hepatitis B immunization policy were selected using a stratified random cluster sampling strategy from January to December 2015. A total of 72 623 eligible children participated in the study, which included a questionnaire survey and blood tests (0.3 mL vein blood) for HBsAg and anti-HBs with ELISA method. Repeated tests were performed on the blood samples with a HBsAg positive result. Results About 0.24% of the children were HBsAg positive; 64.50% were anti-HBs positive; 35.26% were both HBsAg and anti-HBs negative. The standardized rates based on the 2010 population census were: 0.24% HBsAg positive, 64.05% anti-HBs positive, and 35.71% both HBsAg and anti-HBs negative. HBsAg positive rates increased with age, ranging from 0% to 0.65% (P<0.001). Rural children had a higher HBsAg positive rate (0.32%) than their urban counterparts (0.16%, P<0.001). Those with a family history of Hepatitis B had a higher HBsAg positive rate (1.53%) than those without a family history (0.22%, P<0.001). Anti-HBs positive rates decreased withage, ranging from 47.85% to 71.43% (P<0.001). Rural children had a lower anti-HBs positive rate (62.06%)than their urban counterparts (66.81%, P<0.001). The prevalence of both HBsAg and anti-HBs negative cases increased with age, ranging from 28.57% to 51.98% (P<0.001). Rural children had a higher rate of both HBsAg and anti-HBs negative (37.62%) than their urban counterparts (33.03%, P<0.001). About 35.37% of the children who had negative HBsAg and anti-HBs had not received Hepatitis B immunization. Conclusions Hepatitis B vaccinations are highly effective in Mianyang. However, there are disparities in anti-HBs positive rates between the children with different characteristics. A certain proportion of children are still susceptible to hepatitis B infection. It is necessary to attach importance to neonatal hepatitis B vaccination, surveillance on anti-HBs, and strengthened immunization for the children who are lack of antibody protection.  
    • HTML全文
© 2018 《koko体育app 学报（医学版）》编辑部　版权所有 cc

开放获取💧 本文遵循知识共享署名—非商业性使用4.0国际许可协议（CC BY-NC 4.0），允许第三方对本刊发表的论文自由共享（即在任何媒介以任何形式复制、发行原文）、演绎（即修改、转换或以原文为基础进行创作），必须给出适当的署名，提供指向本文许可协议的链接，同时标明是否对原文作了修改；不得将本文用于商业目的。CC BY-NC 4.0许可协议详情请访问

/

返回文章
返回
var _hmt = _hmt || []; (function() { var hm = document.createElement("script"); hm.src = "https://hm.baidu.com/hm.js?90c4d9819bca8c9bf01e7898dd269864"; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(hm, s); })(); !function(p){"use strict";!function(t){var s=window,e=document,i=p,c="".concat("https:"===e.location.protocol?"https://":"http://","sdk.51.la/js-sdk-pro.min.js"),n=e.createElement("script"),r=e.getElementsByTagName("script")[0];n.type="text/javascript",n.setAttribute("charset","UTF-8"),n.async=!0,n.src=c,n.id="LA_COLLECT",i.d=n;var o=function(){s.LA.ids.push(i)};s.LA?s.LA.ids&&o():(s.LA=p,s.LA.ids=[],o()),r.parentNode.insertBefore(n,r)}()}({id:"K9y7iMpaU8NS42Fm",ck:"K9y7iMpaU8NS42Fm"}); koko体育-koko体育app koko体育-koko体育网页版koko体育app koko体育-全站app下载(官网) m6米乐app|下载 m6米乐app|主頁欢迎您!!