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许彬彬, 苟泽辉, 周莉等. 创伤性骨折患者高密度脂蛋白水平与深静脉血栓相关性的研究[J]. koko体育app 学报（医学版）, 2019, 50(2): 248-251.
引用本文: 许彬彬, 苟泽辉, 周莉等. 创伤性性粉碎性骨折病患者高相对密度脂蛋白a质级别与深动脉血栓相应性的论述[J]. 重庆大学时学报（医疗版）, 2019, 50(2): 248-251.
XU Bin-bin, GOU Ze-hui, ZHOU Li.et al. Low Plasma High Density Lipoprotein-cholesterol Level Associated with Deep Vein Thrombosis in Traumatic[J]. Journal of Sichuan University (Medical Sciences), 2019, 50(2): 248-251.
Citation: XU Bin-bin, GOU Ze-hui, ZHOU Li.et al. Low Plasma High Density Lipoprotein-cholesterol Level Associated with Deep Vein Thrombosis in Traumatic[J]. Journal of Sichuan University (Medical Sciences), 2019, 50(2): 248-251.

创伤性骨折患者高密度脂蛋白水平与深静脉血栓相关性的研究

Low Plasma High Density Lipoprotein-cholesterol Level Associated with Deep Vein Thrombosis in Traumatic

  • 摘要: 目的探讨创伤性骨折患者血清高密度脂蛋白（HDL-C）水平与深静脉血栓形成的相关性。方法对2012年4月至2014年12月1 054例创伤性骨折患者进行回顾性研究。按超声筛查结果，分为深静脉血栓组188例，对照组866例，采用单因素和多因素logistic回归分析HDL-C水平与深静脉血栓形成的关系。结果深静脉血栓组的血清HDL-C水平低于对照组，HDL-C水平与深静脉血栓形成相关。HDL-C水平降低、年龄增大、制动时间增加、筛查前未用抗凝药时间增加、输血均是创伤性骨折患者深静脉血栓形成的危险因素；骨折部位不同，形成深静脉血栓的风险不同。深静脉血栓组和对照组中，手术患者较未行手术患者血清HDL-C水平降低。结论 创伤性骨折患者血清HDL-C水平与深静脉血栓形成独立相关。  
    Abstract: ObjectiveTo explore the association of plasma high density lipoprotein-cholesterol (HDL-C) and deep vein thrombosis (DVT) in traumatic fracture patients. MethodsWe performed a retrospective study in 1 054 traumatic fracture patients admitted between April 2012 and December 2014. 188 cases were divided into DVT and others (n=866) into control group based on ultrasound results. The relationship between HDL-C and DVT was determined by univariate and multivariate logistic regression analyses. ResultsCompared with control group,patients in DVT group had significantly lower HDL-C level,and low level of plasma HDL-C was associated with the occurrence of DVT. Deceased HDL-C,inceased age,inceased immobilization,inceasd anticoagulant-free days,fracture sites,and blood transfusion were risk factors for the occurrence of DVT in traumatic fracture patients. Patients with surgery had significantly lower level of HDL-C in both groups compared with patients without surgery respectively. ConclusionLow level of plasma HDL-C was independently associated with the occurrence of DVT in traumatic fracture patients.  
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