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王业, 朱辉, 杨赛等. 支气管内超声引导针吸活检术对肺门、纵隔淋巴结肿瘤和结核的诊断价值[J]. koko体育app 学报（医学版）, 2017, 48(3): 347-351.
引用本文: 王业, 朱辉, 杨赛等. 支气管径超音波正确引导针吸活检术对肺门、纵隔淋巴结节结淋巴肿瘤和结核的初步判断交换价值[J]. 云南二本大学学报（医学研究版）, 2017, 48(3): 347-351.
WANG Ye, ZHU Hui, YANG Sai. et al. The Diagnostic Value of Endobronchial Ultrasound-guided Needle Aspiration Biopsy for Lung or Mediastinal[J]. Journal of Sichuan University (Medical Sciences), 2017, 48(3): 347-351.
Citation: WANG Ye, ZHU Hui, YANG Sai. et al. The Diagnostic Value of Endobronchial Ultrasound-guided Needle Aspiration Biopsy for Lung or Mediastinal[J]. Journal of Sichuan University (Medical Sciences), 2017, 48(3): 347-351.

支气管内超声引导针吸活检术对肺门、纵隔淋巴结肿瘤和结核的诊断价值

The Diagnostic Value of Endobronchial Ultrasound-guided Needle Aspiration Biopsy for Lung or Mediastinal

  • 摘要: 目的探讨支气管内超声引导针吸活检术（EBUS-TBNA）在肺门、纵膈淋巴结恶性肿瘤和结核诊断中的应用价值。方法回顾性分析2013年1月至2016年9月在koko体育app 华西医院呼吸内镜中心接受EBUS-TBNA检查的553例患者的临床及病理资料，统计EBUS-TBNA对肺门、纵膈淋巴结肿瘤和结核的诊断敏感性、特异性和准确率。结果EBUS-TBNA诊断肺门、纵膈淋巴结恶性肿瘤的敏感性、特异性和准确率分别为89.2%（263/295）、100.0%（247/247）和94.1%（510/542）。针吸活检组织查见肉芽肿诊断结核的敏感性、特异性和准确率分别为65.0%（76/117）、97.2%（385/396）和89.9%（461/513）。标本组织行抗酸染色和TB-PCR的102例中，查见抗酸杆菌或TB-PCR任一项阳性诊断结核的敏感性、特异性和诊断准确率为63.7%（58/91）、90.9%（10/11）和66.7%（68/102）。结论EBUS-TBNA诊断肺门和纵膈肿瘤具有较高的敏感性和特异性，并可联合抗酸染色和TB-PCR联合诊断肺门和纵膈淋巴结结核。  
    Abstract: Objective To determine the value of endobronchial ultrasound-guided transbronchial needle aspiration （EBUS-TBNA） in diagnosing lung or mediastinal lymph node cancer and tuberculosis. Methods Clinical and pathological data of 553 patients who underwent EBUS-TBNA from January 2013 to September 2016 in West China Hospital of Sichuan University were reviewed. The sensitivity, specificity and accuracy of EBUS-TBNA for diagnosing lymph node tumor and tuberculosis of hilar and mediastinal lymph nodes were calculated. Results The sensitivity, specificity and accuracy of EBUS-TBNA in diagnosing hilar and mediastinal lymph node cancer were 89.2% (263/295), 100% (247/247) and 94.1% (510/542), respectively, compared with 70% (76/117), 97.2% (385/396) and 89.9% (461/513), respectively, for diagnosing tuberculosis identified though granulomatous biopsy. In the 102 cases with acid fast staining and TB-PCR, 63.7% accuracy (58/91), 90.9% (10/11) sensitivity and 66.7% (68/102) specificity were found for any positive findings from acid fast bacilli or TB-DNA. Conclusion EBUS-TBNA has high sensitivity and specificity for diagnosing hilar and mediastinal tumor, which can be used in combination with acid fast staining and TB-PCR for diagnosing tuberculosis.  
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