koko体育app

欢迎来到《koko体育app 学报（医学版）》
王朴, 魏晓霏, 阳筱甜等. 全身振动治疗对兔膝骨关节炎早期软骨下骨结构与功能重塑的影响[J]. koko体育app 学报（医学版）, 2014, 45(1): 111-115.
引用本文: 王朴, 魏晓霏, 阳筱甜等. 身体机械振动治療对兔膝骨软骨炎之前软骨下骨机构与工作再造的影响到[J]. 河北读书学报（医学检验版）, 2014, 45(1): 111-115.
WANG Pu, WEI Xiao-fei, YANG Xiao-tian. et al. Effects of Whole Body Vibration on Structural and Functional Remodeling of Subchondral Bones in[J]. Journal of Sichuan University (Medical Sciences), 2014, 45(1): 111-115.
Citation: WANG Pu, WEI Xiao-fei, YANG Xiao-tian. et al. Effects of Whole Body Vibration on Structural and Functional Remodeling of Subchondral Bones in[J]. Journal of Sichuan University (Medical Sciences), 2014, 45(1): 111-115.

全身振动治疗对兔膝骨关节炎早期软骨下骨结构与功能重塑的影响

Effects of Whole Body Vibration on Structural and Functional Remodeling of Subchondral Bones in

  • 摘要: 目的 研究全身振动治疗（WBVT）对兔膝骨关节炎软骨下骨结构与功能重塑的影响。 方法 新西兰兔24只，随机分为膝关节前交叉韧带切断术（ACLT组）和WBVT+ACLT组，每组12只。两组行左侧ACLT，制备膝骨关节炎模型。术后2个月WBVT+ACLT组实施WBVT。振动治疗参数为：频率40 Hz，振动幅度2~4 mm，40 min/d，5 d/周，持续治疗4周。治疗完成后，取两组动物左侧膝股骨和胫骨置于 Micro-CT 系统进行扫描，应用Micview V2.1.2三维重建处理软件和 ABA 专用骨骼分析软件对股骨髁和胫骨平台骨小梁体积分数（BVF）、骨小梁厚度（Tb.Th）、骨小梁分离度（Tb.Sp）、骨小梁数量(Tb.N)、体积骨密度（vBMD）和组织骨密度（tBMD）进行检测。应用 Geomagic Studio 11.0 软件换算股骨髁和胫骨平台弹性模量（EM）、反应力（RF）和平均Von Miss应力（VMF）。 结果 显微CT成像结果发现：ACLT组软骨下骨骨小梁出现稀疏表现并呈现断裂现象，部分骨小梁排列紊乱，结构扭曲。关节边缘处见不同程度的椭圆形或圆形骨赘形成。WBVT+ACLT组软骨下骨骨小梁虽然也出现稀疏断裂的现象，但直观上较ACLT组骨小梁排列较为整齐有序，少见结构性扭曲。WBVT+ACLT组与ACLT组相比较， BVF、Tb.N、Tb.Th，股骨的EM、RF和VMF升高(P<0.05)；Tb.Sp减少(P<0.05)。骨密度（vBMD和tBMD）增加(P<0.05)。 结论 WBVT可有效改善兔膝骨关节炎早期阶段软骨下骨微结构和力学性能，起到保护进展性骨关节炎软骨下骨微损伤和力学性能降低的作用。  
    Abstract: Objective? To investigate the effects of whole body vibration therapy (WBVT) on structural and functional remodeling of subchondral bone in rabbits with early Osteoarthritis (OA). Methods? Twenty-four adult rabbits received anterior cruciate ligament transaction (ACLT) to establish knee osteoarthritis model. The rabbits were randomly divided into two groups: ACLT group and WBVT+ACLT group. The rabbits in the WBVT+ACLT group received whole body vibration treatment (Frequency:40 Hz;Amplitude: 2-4 mm;40 min/d，5 d/week，4 weeks) two months after surgery. After interventions, the left femur and tibia of all rabbits were placed in a Micro-CT scanning system. The bone volume fraction (BVF), trabecular thickness (Tb.Th), trabecular spacing (Tb.Sp), trabecular number (Tb.N), volumetric BMD (vBMD), and tissue BMD (tBMD) of the bones of femoral condyle and tibia were analysed using three-dimensional reconstruction Micview V2.1.2 and ABA analysis software. Geomagic Studio 11.0 software were used to calculate modulus (EM), reaction force (RF) and average Von Miss stress (VMF). Results? Higher levels of BVF, Tb.N, Tb.Th, EM, RF, VMF, vBMD and tBMD and lower levels of Tb.Sp were found in distal femora and tibia of the rabbits in the WBVT+ACLT group compared with the controls (P＜0.05). Conclusion? WBVT can effectively improve bone microstructure and mechanical properties of rabbits with early knee osteoarthritis.  
    • HTML全文
© 2014 《koko体育app 学报（医学版）》编辑部　版权所有 cc

开放获取ꦡ 本文遵循知识共享署名—非商业性使用4.0国际许可协议（CC BY-NC 4.0），允许第三方对本刊发表的论文自由共享（即在任何媒介以任何形式复制、发行原文）、演绎（即修改、转换或以原文为基础进行创作），必须给出适当的署名，提供指向本文许可协议的链接，同时标明是否对原文作了修改；不得将本文用于商业目的。CC BY-NC 4.0许可协议详情请访问

/

返回文章
返回
var _hmt = _hmt || []; (function() { var hm = document.createElement("script"); hm.src = "https://hm.baidu.com/hm.js?90c4d9819bca8c9bf01e7898dd269864"; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(hm, s); })(); !function(p){"use strict";!function(t){var s=window,e=document,i=p,c="".concat("https:"===e.location.protocol?"https://":"http://","sdk.51.la/js-sdk-pro.min.js"),n=e.createElement("script"),r=e.getElementsByTagName("script")[0];n.type="text/javascript",n.setAttribute("charset","UTF-8"),n.async=!0,n.src=c,n.id="LA_COLLECT",i.d=n;var o=function(){s.LA.ids.push(i)};s.LA?s.LA.ids&&o():(s.LA=p,s.LA.ids=[],o()),r.parentNode.insertBefore(n,r)}()}({id:"K9y7iMpaU8NS42Fm",ck:"K9y7iMpaU8NS42Fm"}); koko体育-koko体育app koko体育-koko体育网页版koko体育app koko体育-全站app下载(官网) m6米乐app|下载 m6米乐app|主頁欢迎您!!