koko体育app

欢迎来到《koko体育app 学报（医学版）》
魏腾达, 李顺品, 刘云兴等. 钒作业工人的氧化应激水平研究[J]. koko体育app 学报（医学版）, 2015, 46(6): 856-859.
引用本文: 魏腾达, 李顺品, 刘云兴等. 钒上班劳务工的空气氧化应激性水准深入分析[J]. 河南读书学报（生物学版）, 2015, 46(6): 856-859.
WEI Teng-da, LI Shun-pin, LIU Yun-xing. et al. Oxidative Stress Level of Vanadium-exposed Workers[J]. Journal of Sichuan University (Medical Sciences), 2015, 46(6): 856-859.
Citation: WEI Teng-da, LI Shun-pin, LIU Yun-xing. et al. Oxidative Stress Level of Vanadium-exposed Workers[J]. Journal of Sichuan University (Medical Sciences), 2015, 46(6): 856-859.

钒作业工人的氧化应激水平研究

Oxidative Stress Level of Vanadium-exposed Workers

  • 摘要: 目的 评价钒暴露作业工人外周血氧化应激水平，为研究钒对神经系统的影响机制提供人群资料。方法 采用整群抽样的方法纳入86例接钒工人，65例对照工人。自制问卷收集人口学基本信息及职业暴露资料，试剂盒法检测目标人群外周血血清样本中的氧化应激水平〔超氧化物歧化酶（SOD），丙二醛（MDA），诱导型一氧化氮合酶（iNOS）〕。比较接钒工人和对照工人血清氧化应激水平的差异。 结果 接钒工人血清中MDA含量高于对照工人（ P<0.05），总超氧化物歧化酶（T-SOD）活性低于对照工人（ P<0.05）, 其中锰超氧化物歧化酶（Mn-SOD）活性降低明显（ P<0.05），而铜锌超氧化物歧化酶（CuZn-SOD）活性无明显变化（ P>0.05）。接钒工人和未接钒工人血清中的iNOS活性比较接近，差异无统计学意义（ P>0.05）。结论 钒暴露可能会影响作业工人的脂质过氧化，显著降低机体的抗氧化水平。目前尚不能确定钒与活性氮损伤之间的关系。  
    Abstract: Objective To determine the relationship between lesion locations and quality of life (QOL) in patients with ischemic stroke. Methods The QOL of 456 stroke survivors was assessed two years after the occurrence of stroke. The EQ-5D was used for measuring QOL. Lesion locations of the patients were identified with CT, MRI and clinical features. Risk factors associated with QOL were identified using a multi-level model. Results Among the 456 stroke survivors, 61.62% (3/5) had ACI lesions, and more than half of ACI occurred in the subcortex. The number of stroke survivors with left and right hemisphere lesions was almost equal. Different QOL was found between stroke survivors with a right-side brain lesion and those with non-brain lesions ( P＜0.001). Significant differences in QOL were also found between those with a subcortex of anterior circulation lesion and others ( P＜0.044). Conclusion Lesion locations are associated with QOL. Future studies should pay attention to lesion locations classified by vascular territory and brain anatomical structures and size of lesions.  
    • HTML全文
© 2015 《koko体育app 学报（医学版）》编辑部　版权所有 cc

开放获取ꦯ 本文遵循知识共享署名—非商业性使用4.0国际许可协议（CC BY-NC 4.0），允许第三方对本刊发表的论文自由共享（即在任何媒介以任何形式复制、发行原文）、演绎（即修改、转换或以原文为基础进行创作），必须给出适当的署名，提供指向本文许可协议的链接，同时标明是否对原文作了修改；不得将本文用于商业目的。CC BY-NC 4.0许可协议详情请访问

/

返回文章
返回
var _hmt = _hmt || []; (function() { var hm = document.createElement("script"); hm.src = "https://hm.baidu.com/hm.js?90c4d9819bca8c9bf01e7898dd269864"; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(hm, s); })(); !function(p){"use strict";!function(t){var s=window,e=document,i=p,c="".concat("https:"===e.location.protocol?"https://":"http://","sdk.51.la/js-sdk-pro.min.js"),n=e.createElement("script"),r=e.getElementsByTagName("script")[0];n.type="text/javascript",n.setAttribute("charset","UTF-8"),n.async=!0,n.src=c,n.id="LA_COLLECT",i.d=n;var o=function(){s.LA.ids.push(i)};s.LA?s.LA.ids&&o():(s.LA=p,s.LA.ids=[],o()),r.parentNode.insertBefore(n,r)}()}({id:"K9y7iMpaU8NS42Fm",ck:"K9y7iMpaU8NS42Fm"}); koko体育-koko体育app koko体育-koko体育网页版koko体育app koko体育-全站app下载(官网) m6米乐app|下载 m6米乐app|主頁欢迎您!!