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陈文杰, 魏静, 陈廷涛. 益生菌对癌症治疗副作用的改善效果：回顾与展望[J]. koko体育app 学报（医学版）, 2022, 53(3): 532-537. DOI:
引用本文: 陈文杰, 魏静, 陈廷涛. 益生菌对癌症治疗副作用的改善效果：回顾与展望[J]. koko体育app 学报（医学版）, 2022, 53(3): 532-537. DOI:
CHEN Wen-jie, WEI Jing, CHEN Ting-tao. Probiotics' Ameliorating Effect on Side Effects of Cancer Treatment: Reflections and Prospects[J]. Journal of Sichuan University (Medical Sciences), 2022, 53(3): 532-537. DOI:
Citation: 🐷 CHEN Wen-jie, WEI Jing, CHEN Ting-tao. Probiotics' Ameliorating Effect on Side Effects of Cancer Treatment: Reflections and Prospects[J]. Journal of Sichuan University (Medical Sciences), 2022, 53(3): 532-537. DOI:

益生菌对癌症治疗副作用的改善效果：回顾与展望

Probiotics' Ameliorating Effect on Side Effects of Cancer Treatment: Reflections and Prospects

  • 摘要: 当前癌症治疗方案主要包括手术切除、放射治疗、化学治疗和免疫治疗，上述疗法在延长患者生存期的同时，往往伴有多种副作用。肠道微生物在人体健康和疾病发生发展中扮演了重要的角色，参与了宿主近乎所有的生理生化进程。作为一种外源性干预，益生菌具有预防疾病、增强免疫力等作用，其自身抗癌能力和对癌症治疗副作用改善效果正逐渐得到认可和重视。本文通过总结近年来研究肠道菌群与肿瘤发生发展的相关进展，重点讨论了益生菌在改善肿瘤各种疗法副作用方面的应用，期望能为益生菌在癌症治疗的临床使用提供有益参考。  
    Abstract: Surgical resection, radiotherapy, chemotherapy, and immunotherapy are the main therapies for cancers. These cancer therapies all prolong patient survival, but also bring multiple side effects. Gut microbiota participates in almost all the physiological and biochemical processes of the host, playing a key role in human health and diseases. As an exogenous intervention, probiotics can prevent diseases and enhance immunity. Their anti-cancer ability and ameliorative effect have received increasing recognition. Herein, we reported the latest findings on gut microbiota and cancer pathogenesis, focusing on the application of probiotics in reducing the side effects caused by cancer therapies and hoping to provide supportive references for the clinical use of probiotics in cancer treatment.  
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