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薛斯亮, 杨洁, 吕熙. 藻酸钙敷料对甲手术创面愈合的临床研究[J]. koko体育app 学报(医学版), 2018, 49(4): 652-655.
引用本文: 薛斯亮, 杨洁, 吕熙. 藻酸钙敷料对甲介入手术创面康复的诊疗调查[J]. 贵州读书学报(医美版), 2018, 49(4): 652-655.
XUE Si-liang, YANG Jie, LÜ Xi. The Evaluation of Calcium Alginate Dressing Helping Wound Healing of Nail Surgery[J]. Journal of Sichuan University (Medical Sciences), 2018, 49(4): 652-655.
Citation: XUE Si-liang, YANG Jie, LÜ Xi. The Evaluation of Calcium Alginate Dressing Helping Wound Healing of Nail Surgery[J]. Journal of Sichuan University (Medical Sciences), 2018, 49(4): 652-655.

藻酸钙敷料对甲手术创面愈合的临床研究

The Evaluation of Calcium Alginate Dressing Helping Wound Healing of Nail Surgery

  • 摘要: 目的 评价藻酸钙敷料对甲手术创面愈合的作用。 方法 纳入2016年8月至2017年12月在koko体育app 华西医院皮肤科因甲床疾病需切除部分拇趾甲床患者40例。患者由随机数字表分配到对照组和藻酸钙敷料组,每组20例,藻酸钙敷料组在甲手术后使用藻酸钙敷料覆盖创面,对照组甲手术后使用凡士林纱布覆盖后纱布包扎。术后每24 h评估一次创面出血的例数和疼痛评分采用视觉疼痛标尺(VAS)评分,共评估3次;记录每个患者的中位疼痛持续时间、创面愈合(手术后创面无渗出、完全干燥)时间。 结果 对照组男性16例,女性4例,藻酸钙敷料组男性12例,女性8例,对照组平均年龄(37.45±3.30)岁,藻酸钙敷料组(33.40±3.13)岁,两组性别比、年龄差异无统计学意义(P>0.05)。治疗过程中藻酸钙敷料组未见感染,对照组出现1例感染。甲手术治疗后24 h换药时,藻酸钙敷料组出血例数和VAS评分低于对照组(P<0.05)。48 h换药时,藻酸钙敷料组无人出血,而对照组仍有2例出血(P>0.05);VAS评分低于对照组,两组VAS评分差异有统计学意义(P<0.05)。72 h换药时,两组均未见出血,两组VAS评分差异无统计学意义(P>0.05)。藻酸钙敷料组中位疼痛持续时间为24 h,对照组为72 h。甲手术后创面愈合时间,对照组需要(11.35±1.72)d,藻酸钙敷料组则需要(9.40±2.30)d,两者差异有统计学意义(P<0.05)。 结论 术后使用藻酸钙敷料可以促进甲手术后创面恢复,减轻出血和疼痛。  
    Abstract: Objective To determine the effect of calcium alginate dressing therapy on wound healing after nail surgery. Methods Patients with nail surgery on nail bed of great toe were divide into two groups (20 caces for each group) randomly based on random number table. Calcium alginate dressing were used in treatment group after nail surgery and the vaseline gauze were applied in control group after surgery. The number of wound remain bleeding and the rating of painvisual analogue scale (VAS) scores were observed for three times (24 h, 48 h and 72 h). Median time of pain bearing and time of wound healing were also observed. Results There were 16 males and 4 females in control groupmean age (37.45±3.30) yr.. There were 12 males and 8 females in treatment groupmean age (33.40±3.13) yr.. There were no significant differences in sex ratio and age between the two groups (P>0.05). No infection was found in the treatment group, but 1 case in the control group. The number of bleeding cases in treatment group was less than that in control group (P<0.05), as well as the VAS scores 24 h after nail surgery (P<0.05). At 48 h, no bleeding occurred in the traetment group, while there were 2 cases of bleeding in the control group (P>0.05); the VAS score in treatment group was less than that in control group (P<0.05). At 72 h, no bleeding was observed in both groups, and the difference in VAS score between the two groups was not statistically significant (P>0.05). The median time of pain bearing was 24 h in treatment group while 72 h in control group. Wound healing time of treatment group (9.40 d) and control group (11.35 d) was statistically significant (P<0.05). Conclusion Calcium alginate dressing therapy can promote postoperative wound recovery and block bleeding and pain after nail surgery.  
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